Quenching enzyme - aquatic special compound enzymesThe harm of gram-negative bacteria to aquatic animals:According to gram staining, bacteria can be divided into gram negative bacteria and gram positive bacteria. Among them, a lot of important pathogenic bacteria related to aquatic animal belongs to gram-negative bacteria. Gram-negative bacterial disease, as the most serious disease harming aquatic animals in China, which has a lot of pathogenic species and harm widely endemic areas aquatic breeding category, has caused great economic losses in aquaculture. The pathogen  which causes bacterial disease of aquatic animals has vibrio anguillarum, Vibrio parahaemolyticus,algin vibrio, Aeromonas punctata, Aeromonas hydrophila, Flavobacterium columnare,Edwardsiella tarda, etc, see table 1.Tab. 1 Main gram-negative bacteria of aquatic pathogenicQuorum sensing and gram-negative bacteria quenching enzymes:Intestinal bacteria often produces and releases specific extracellular signal molecules in the gastrointestinal tract, signaling molecules accumulating to a certain concentration, can induce bacteria control bacteria molecular and cellular response, which is called bacterial quorum sensing. Quorum sensing plays an important role to maintain the normal function of bacteria, and regulate gene expression,as shown in figure 1. Quenching enzyme can degrade gram-negative bacterial quorum sensing signal molecules, destroy the quorumsensing, influence bacteria colonize, break biofilm fo...
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