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Chemical and Physical DataEnzyme Activity1,500U/g, 3,000U/g, 100,000U/g Appearance White or light yellow mini-granuleParticle size125~300μmLoss on Drying: Not more than 10%Enzyme Activity DefinitionOne β-mannanase activity unit (U) is defined as the amount of enzyme which liberates 1µmol reducing sugar from 5 mg/ml Locust bean gum(LBG) solution per minute at 37℃ and pH 5.5 under the conditions of the test.Functions  Ø Degrade mannan to MOS, and improve the utilization of dietary energy. Ø Improve the gastrointestinal microbial flora, enhance the integrity of intestinal mucosa.Ø Enhance the utilization of soybean meal, cottonseed meal and palm meal, improve the animal performance.Ø Reduce the viscosity of the contents in digestive tract, improve the growth uniformity of livestock and poultry.Ø Destroy the structure of cell wall in plant feed, and improve...
Acid β-mannanaseβ-mannan is a kind of hemicellulose which is most widely spread and has high content in plant except cellulose and xylan. It is a linear polymer formed by β-1,4-D- D-mannose, mainly glucose group, acetylgroup and galactose group, forming the main component of the cell wall of seed plants.β-mannan and its derivatives hinder nutrition absorption in feed, which leads to diarrhea in different degrees, and ultimately affects the growth and feed utilization of livestock and poultry. The anti-nutritional effect of mannan is the formation of gel 'mucus' after dissolving it in water, so as to improve the viscosity of chyme, reduce the contact between endogenous enzymes and nutrients in animals, slow down nutrient absorption by intestinal tract, and adsorb metal ions, such as Ca2+、Zn2+、Na+, and endogenous enzymes, which affect the nutrient digestion and absorption. Moreover, mannosan can cause excessive immune response under stress or disease, affect the absorption of glucose by small intestine, interfere carbohydrate metabolism and the secretion of insulin-like growth factor(IGF-1), thus inhibit the growth of animals. Acid β-mannanase is an endomannanase that mainly hydrolyzes galactomannan, glucomannan, galactomannan and mannan, the main chain of which are all 1,4-β-D-pyran mannose, to oligosaccharide which containing 2~10 residues.Challenge Group has been working with the Feed Research Institute of the Chinese Academy of Agricultural Sciences(CAAS) for more t...
Introduction of Challen GOX (Glucose Oxidase)Glucose oxidase catalyzes the reaction of glucose with oxygen to form gluconic acid and hydrogen peroxide, which has a significant antibacterial and bactericidal effect. It is an ideal subsitution of some antibiotics. Beijing Challenge Group and Animal Nutrition and Feed Science Institute of Chinese Academy of Agricultural Sciences have jointly overcome several technical difficulties and developed a brand-new Challen GOX with stronger temperature resistance and better efficacy in animal intestinal environment. Challenge Group is the first enterprise to promote glucose oxidase in feed and breeding industry. By extensive trials, the product is testified to effectively control bacterial diarrhea in animals, to reduce the harm of feed mycotoxins to animal organisms, and improve animal performance. Challen GOX have been used widely in China, North America, Europe and Southeast Asia etc.Chemical and Physical CharacteristicsEnzyme Activity: 5000U/g,10000U/gAppearance: Light yellow power or granulePackage: 25kg/bagShelf Life and Storage: 12 months under proper conditions in a dry, well ventilated and cool place with packaging unopened, away from sunlight. Mode of ActionGlucose oxidase can consume molecular oxygen or atomic oxygen, oxidize glucose, and protect oxidizable components in feed. According to the reaction conditions, there are three forms of Glucose oxidase catalytic reaction :1 mol of oxygen is consumed when oxidize per 1 m...
Product NameGlucose OxidaseEnzyme Activity1,000U/g,2000U/gAppearance Light yellow granuleParticle size125~300μmLoss on Drying Not more than 10%Enzyme Activity DefinitionOne glucose oxidase activity unit(U) is defined as the amount of enzyme which oxidizes 1µmol β-D- glucose into D-gluconic acid and H2O2 at 30℃ and pH 6.0 under the conditions of the test.FunctionsØ Produce gluconic acid and hydrogen peroxide in intestinal tract, reduce the gastrointestinal acidity, and restrain the pathogen.Ø Maintain the integrity of intestinal epithelial cells, and resist pathogen’s invasion.Ø Improve the acid digestion environment in intestinal tract, relieve the poisoning caused by mycotoxin and other drugs.Ø Reduce the use of acidifiers and antibiotics, save the feed cost.Recommended Dosage of Glucose Oxidase 1000 U/gSpeciesAdd amount(compound feed)U/kgg/tPiglet200~300200~300Growing pig100~200100~200Finishing pig100~200100~200Broiler 200~3...
Xylanase, adopted the liquid submerged fermentation technology, with excellent post-treatment process,has characters of high activity, high stability and high degradation. Xylanase, a kind of enzyme whichdegrades the linear polysaccharide beta-1,4-xylan into xylose, contains endo β- Xylanase, exterior β- Xylanase and xylo-disaccharide glycosidase. Xylanase can also degrade anti-nutritional factors araboxylan efficiently, decrease prescription cost, enhance the productivity performance and disease resistance of animals, and reduce the pollution of animal excretion.                                              Chemical Structure ChartChemical and Physical DataEnzyme Activity50,000U/g and 100,000U/g, 400,000U/gAppearance White or light yellow mini-granuleParticle size125~300μmLoss on DryingNot more than 10%Enzyme Activity DefinitionOne xylanase activity unit (U) is defined as the amount of&...
Chemical and Physical DataEnzyme Activity1,000U/g~3,000U/g AppearanceWhite or light yellow powderParticle size125~300μmLoss on DryingNot more than 10%Enzyme Activity DefinitionOne α-galactosidase activity unit (U) is defined as the amount of enzyme which liberates 1µmol 4-nitrophenol from 4-nitrophenol α- D - pyran galactoside solution with the concentration of 10mM per minute at 37℃ and pH 5.5 under the conditions of the test.Functions Efficiently degrade the raffinose, stachyose and other anti-nutrients, reduce the animal diarrhea.Maintain high enzyme activity in animal gastrointestinal tract.Promote the utilization of amino acid, soybean meal and other energy, improve the animal performance.Restrain the excessive fermentation of microorganisms in intestinal tract, reduce the poisoning of pathogens, and enhance the immunity.Destroy the structure of cell wall, promote the release of nutrients in the cell. Maintain high stability in the process of feed storage.Recommended Dosage of α-galactosidase 1000 U/g60~100g/MT in feedPackage25kg per bagUsage and StorageThis enzyme can use with xylanase, β- mannase and β- glucanase.Seal both internal and external package after use.Shelf Life12 months from date of production under proper conditions in a dry,well ventilated and cool place. There’s synergistic effect when α- galactosidase is applied with β- glucanase and β-mannanase. Application: granule concentrates and premix of bean pulp, miscellan...
Chemical and Physical DataEnzyme Activity50,000U/g, 100,000U/gAppearanceWhite or light yellow mini-granuleParticle size125~300μmOptimum pH range1.5~6.5Available pH range 3.0~10.0Optimum Temperature range30~70℃Optimum Temperature65℃Loss on DryingNot more than 10%Enzyme Activity DefinitionOne β-glucanase activity unit (U) is defined as the amount of enzyme which liberates 1µmol glucose from 0.4% barley glucan solutionper minute under the conditions of 37℃ and PH 5.5.Functions Ø Degrade glucan in wheat/barley diets, and improve diets’ digestibility. Ø Destroy the cell wall of plant, and improve the absorption of nutrients.Ø Reduce the viscosity of β-glucan, improve the ecological environment and morphology of animal digestive tract.Ø Increase the activity of endogenous enzyme in animal intestinal tract.Ø Adjust poultry’s neuroendocrine system, promote its growth and enhance the immunity.Recommended Dosage of beta-glucanase10,000U/g:80~150g/MT i...
Aquatic Phytase—Neutral Thermostable phytasePlant material of aquatic feed contains a large number of phytic acid phosphorus, which cannot be utilized by aquatic animals, and chelate Zn, Fe, Ca and other mineral elements, amino acids, starch and other nutrients. Phytic acid and its chelate cannot be degraded in aquatic animal intestines, and large amount of nutrients such as phosphorus and nitrogen emits into directly into water bodies, which exacerbate the eutrophication of water, lead to aquatic animals living environmental deterioration by reason of microbial breeding and a lack of oxygen. The phytase has been widely used in livestock and poultry feed, but because of the huge difference of physiological structure and living environment, which makes the application of phytase in aquaculture feed has been controversial.  So far, Challenge Group has successfully solved the three major bottleneck of phytase in the use of aquatic feed.    Play a role in neutral intestinal condition of aquatic animal.    Resist high temperature of aquatic feed processing and granulating    Play a role in aquatic animals at low temperature of 20~30℃Product Formulations and Enzyme Activity DefinitionAquatic Special Phytase1,000U/g~3,000U/gEnzyme Activity DefinitionOne phytase activity unit (U) is defined as the amount of enzyme which liberates 1µmol inorganic phosphorus from 5.0mmol/L sodium phytate solution per minute at pH 7.0 and 30℃ under ...
Quenching enzyme - aquatic special compound enzymesThe harm of gram-negative bacteria to aquatic animals:According to gram staining, bacteria can be divided into gram negative bacteria and gram positive bacteria. Among them, a lot of important pathogenic bacteria related to aquatic animal belongs to gram-negative bacteria. Gram-negative bacterial disease, as the most serious disease harming aquatic animals in China, which has a lot of pathogenic species and harm widely endemic areas aquatic breeding category, has caused great economic losses in aquaculture. The pathogen  which causes bacterial disease of aquatic animals has vibrio anguillarum, Vibrio parahaemolyticus,algin vibrio, Aeromonas punctata, Aeromonas hydrophila, Flavobacterium columnare,Edwardsiella tarda, etc, see table 1.Tab. 1 Main gram-negative bacteria of aquatic pathogenicQuorum sensing and gram-negative bacteria quenching enzymes:Intestinal bacteria often produces and releases specific extracellular signal molecules in the gastrointestinal tract, signaling molecules accumulating to a certain concentration, can induce bacteria control bacteria molecular and cellular response, which is called bacterial quorum sensing. Quorum sensing plays an important role to maintain the normal function of bacteria, and regulate gene expression,as shown in figure 1. Quenching enzyme can degrade gram-negative bacterial quorum sensing signal molecules, destroy the quorumsensing, influence bacteria colonize, break biofilm fo...
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